|Product Overview:||Recombinant mouse Oscar (Asp19-Asn228) protein fused with Fc region of human IgG1 (Pro100-Lys330) at C-terminus was expressed in mouse myeloma cell line.|
|Description:||Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.|
|Bio-activity:||Measured by its binding ability in a functional ELISA. When Bovine Collagen I is coated at 10 µg/mL, Recombinant Mouse OSCAR Fc Chimera binds with an ED50 of 80-640 ng/mL.|
|Molecular Mass:||49 kDa|
|N-terminal Sequence Analysis:||Asp19|
|Endotoxin:||<0.10 EU per 1 μg of the protein by the LAL method.|
|Purity:||>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.|
|Storage:||12 months from date of receipt, ≤ -20 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, ≤ -20 centigrade under sterile conditions after reconstitution.
|Storage Buffer:||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Preservative:||Reconstitute at 500 μg/mL in PBS.|
|Gene Name:||Oscar osteoclast associated receptor [ Mus musculus (house mouse) ]|
|Synonyms:||mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; Oscar; osteoclast associated receptor; osteoclast-associated immunoglobulin-like receptor; ocl178; osteoclast-associated receptor OSCAR|