|Product Overview :||Recombinant mouse Oscar (Asp19-Asn228) protein fused with Fc region of human IgG1 (Pro100-Lys330) at C-terminus was expressed in mouse myeloma cell line.|
|Description :||Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.|
|Form :||Disulfide-linked homodimer|
|Bio-activity :||Measured by its binding ability in a functional ELISA. When Bovine Collagen I is coated at 10 µg/mL, Recombinant Mouse OSCAR Fc Chimera binds with an ED50 of 80-640 ng/mL.|
|Molecular Mass :||49 kDa|
|N-terminal Sequence Analysis :||Asp19|
|Endotoxin :||<0.10 EU per 1 μg of the protein by the LAL method.|
|Purity :||>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.|
|Storage :||12 months from date of receipt, ≤ -20 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, ≤ -20 centigrade under sterile conditions after reconstitution.
|Storage Buffer :||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Preservative :||Reconstitute at 500 μg/mL in PBS.|
|Gene Name :||Oscar osteoclast associated receptor [ Mus musculus (house mouse) ]|
|Official Symbol :||Oscar|
|Synonyms :||mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; Oscar; osteoclast associated receptor; osteoclast-associated immunoglobulin-like receptor; ocl178; osteoclast-associated receptor OSCAR|
|Gene ID :||232790|
|mRNA Refseq :||NM_175632|
|Protein Refseq :||NP_783440|
|UniProt ID :||Q8VBT3|