Recombinant Mouse Osgep Protein, Myc/DDK-tagged

• Cat.No.: Osgep-4617M
• Product Overview: Purified recombinant protein of mouse full-length O-sialoglycoprotein endopeptidase (Osgep), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
• Molecular Mass: 36.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Osgep O-sialoglycoprotein endopeptidase [ Mus musculus (house mouse) ]
• Official Symbol: Osgep
• Synonyms: OSGEP; O-sialoglycoprotein endopeptidase; probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgep; mOsgep; probable O-sialoglycoprotein endopeptidase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep; GCPL-1; PRSMG1; 1500019L24Rik
• Gene ID: 66246
• mRNA Refseq: NM_133676
• Protein Refseq: NP_598437
• UniProt ID: Q8BWU5