Recombinant Mouse Pask Protein, Myc/DDK-tagged
Cat.No. : | Pask-4682M |
Product Overview : | Purified recombinant protein of mouse full-length PAS domain containing serine/threonine kinase (Pask), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate in respiratory regulation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 151.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Pask PAS domain containing serine/threonine kinase [ Mus musculus (house mouse) ] |
Official Symbol : | Pask |
Synonyms : | Pask; PAS domain containing serine/threonine kinase; P; mKIAA0135; PAS domain-containing serine/threonine-protein kinase; PAS-kinase; paskin; EC 2.7.11.1 |
Gene ID : | 269224 |
mRNA Refseq : | NM_080850 |
Protein Refseq : | NP_543126 |
UniProt ID : | Q8CEE6 |
Products Types
◆ Recombinant Protein | ||
PASK-1610H | Recombinant Human PASK Protein, His (Fc)-Avi-tagged | +Inquiry |
PASK-1118H | Recombinant Human PASK Protein (S949-S1323), Tag Free | +Inquiry |
PASK-1119H | Recombinant Human PASK Protein (S949-S1323), GST tagged | +Inquiry |
PASK-6509M | Recombinant Mouse PASK Protein, His (Fc)-Avi-tagged | +Inquiry |
PASK-12383M | Recombinant Mouse PASK Protein | +Inquiry |
◆ Lysates | ||
PASK-3423HCL | Recombinant Human PASK 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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