Species : |
Mouse |
Source : |
Mammalian Cells |
Tag : |
His |
Protein Length : |
Gln35-Gln155, Ser156-Gln692 |
Description : |
Enables apolipoprotein binding activity; lipoprotein particle binding activity; and low-density lipoprotein particle receptor binding activity. Involved in several processes, including cellular response to insulin stimulus; cellular response to starvation; and regulation of neuron apoptotic process. Acts upstream of or within several processes, including low-density lipoprotein receptor particle metabolic process; regulation of low-density lipoprotein particle receptor catabolic process; and triglyceride metabolic process. Located in COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum; and extracellular space. Is expressed in several structures, including alimentary system; cerebellum; genitourinary system; liver; and telencephalon. Human ortholog (s) of this gene implicated in familial hypercholesterolemia and hypobetalipoproteinemia. Orthologous to human PCSK9 (proprotein convertase subtilisin/kexin type 9). |
Form : |
Lyophilized powder/frozen liquid |
Molecular Mass : |
72.38 kDa |
Purity : |
> 90 % as determined by SDS-PAGE |
Notes : |
For research use only. |
Storage : |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : |
Supplied as solution form in PBS or lyophilized from PBS. |
Reconstitution : |
Reconstitute in sterile water for a stock solution. |
Shipping : |
They are shipped out with dry ice/blue ice unless customers require otherwise. |