Recombinant Mouse Pdcd1lg2 protein, Fc-tagged
Cat.No. : | Pdcd1lg2-7000M |
Product Overview : | Recombinant Mouse Pdcd1lg2 (Leu20-Pro219) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Source : | HEK293 |
Species : | Mouse |
Tag : | human IgG1 Fc |
Predicted N Terminal : | Leu20 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 49.2 kDa. As a result of glycosylation, the protein migrates as 60-70 kDa under reducing (R) condition, and 120-140 kDa under non-reducing (NR) condition (SDS-PAGE). |
Protein length : | Leu20-Arg219 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | Pdcd1lg2 |
Official Symbol : | Pdcd1lg2 |
Synonyms : | PDCD1LG2; programmed cell death 1 ligand 2; PD-1 ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; butyrophilin-like protein; programmed death ligand 2; Btdc; B7-DC; PD-L2; F730015O22Rik; MGC124039; MGC124040 |
Gene ID : | 58205 |
mRNA Refseq : | NM_021396 |
Protein Refseq : | NP_067371 |
UniProt ID : | Q9WUL5 |
Products Types
◆ Recombinant Protein | ||
PDCD1LG2-717H | Recombinant Human PDCD1LG2 Protein, IgG1 Fc-tagged | +Inquiry |
PDCD1LG2-716H | Recombinant Human PDCD1LG2 Protein, Fc-tagged | +Inquiry |
PDCD1LG2-11H | Recombinant Human PDCD1LG2 Protein, C-6His-Avi tagged, Biotinylated | +Inquiry |
PDCD1LG2-715H | Recombinant Human PDCD1LG2 Protein | +Inquiry |
PDCD1LG2-269H | Recombinant Human PDCD1LG2 Protein (ECD), His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
PDCD1LG2-1738MCL | Recombinant Mouse PDCD1LG2 cell lysate | +Inquiry |
PDCD1LG2-951CCL | Recombinant Cynomolgus PDCD1LG2 cell lysate | +Inquiry |
PDCD1LG2-2721HCL | Recombinant Human PDCD1LG2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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