Recombinant Mouse Pdzk1 Protein, Myc/DDK-tagged
Cat.No. : | Pdzk1-4784M |
Product Overview : | Purified recombinant protein of mouse full-length PDZ domain containing 1 (Pdzk1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 56.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Pdzk1 PDZ domain containing 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Pdzk1 |
Synonyms : | PDZK1; PDZ domain containing 1; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; NHERF-3; naPi-Cap1; PDZ domain-containing protein 1; CFTR-associated protein of 70 kDa; Na(+)/H(+) exchanger regulatory factor 3; sodium-hydrogen exchanger regulatory factor 3; na/Pi cotransporter C-terminal-associated protein 1; Pdzd1; mPDZK1; AI267131; AI314638; AL022680; D3Ertd537e; 1700023D20Rik; 2610507N21Rik; 4921513F16Rik |
Gene ID : | 59020 |
mRNA Refseq : | NM_021517 |
Protein Refseq : | NP_067492 |
UniProt ID : | Q9JIL4 |
Products Types
◆ Recombinant Protein | ||
PDZK1-4025R | Recombinant Rat PDZK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PDZK1-6624M | Recombinant Mouse PDZK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PDZK1-1075H | Recombinant Human PDZK1 Protein, MYC/DDK-tagged | +Inquiry |
PDZK1-560H | Recombinant Human PDZ domain containing 1, His-tagged | +Inquiry |
PDZK1-30832TH | Recombinant Human PDZK1 | +Inquiry |
◆ Lysates | ||
PDZK1-477HCL | Recombinant Human PDZK1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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