Recombinant Mouse Phlda3 Protein, Myc/DDK-tagged

• Cat.No.: Phlda3-4841M
• Product Overview: Purified recombinant protein of mouse full-length pleckstrin homology like domain, family A, member 3 (Phlda3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
• Molecular Mass: 13.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Phlda3 pleckstrin homology like domain, family A, member 3 [ Mus musculus (house mouse) ]
• Official Symbol: Phlda3
• Synonyms: PHLDA3; pleckstrin homology-like domain, family A, member 3; pleckstrin homology-like domain family A member 3; TDAG/lpl homolog 1; TDAG51/Ipl homolog 1; Tih1
• Gene ID: 27280
• mRNA Refseq: NM_013750
• Protein Refseq: NP_038778
• UniProt ID: Q9WV95