Recombinant Mouse Pi4k2b Protein, Myc/DDK-tagged

• Cat.No.: Pi4k2b-4849M
• Product Overview: Purified recombinant protein of mouse full-length phosphatidylinositol 4-kinase type 2 beta (Pi4k2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 53.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pi4k2b phosphatidylinositol 4-kinase type 2 beta [ Mus musculus (house mouse) ]
• Official Symbol: Pi4k2b
• Synonyms: PI4K2B; phosphatidylinositol 4-kinase type 2 beta; phosphatidylinositol 4-kinase type 2-beta; phosphatidylinositol 4-kinase type II-beta; type II phosphatidylinositol 4-kinase beta; 2610042N09Rik; 4933409G22Rik
• Gene ID: 67073
• mRNA Refseq: NM_025951
• Protein Refseq: NP_080227
• UniProt ID: Q8CBQ5