Recombinant Mouse PLK4 Protein, His (Fc)-Avi-tagged
Cat.No. : | PLK4-6854M |
Product Overview : | Recombinant Mouse PLK4 with His (Fc)-Avi tag was expressed and purified |
- Specification
- Gene Information
- Related Products
- Download
Source : | HEK293 |
Species : | Mouse |
Tag : | His&Fc&Avi |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | ≥85% by SDS-PAGE |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | PBS buffer |
Gene Name : | Plk4 polo-like kinase 4 [ Mus musculus ] |
Official Symbol : | PLK4 |
Gene ID : | 20873 |
mRNA Refseq : | NM_011495.2 |
Protein Refseq : | NP_035625.2 |
UniProt ID : | Q64702 |
Products Types
◆ Recombinant Protein | ||
PLK4-01H | Recombinant Human PLK4 (G95L) Protein, GST-tagged | +Inquiry |
PLK4-39H | Recombinant Active Human PLK4 (G95L) Mutant Protein, GST-tagged | +Inquiry |
PLK4-1166H | Recombinant Human PLK4 Protein (G581-G808), Tag Free | +Inquiry |
PLK4-1167H | Recombinant Human PLK4 Protein (G581-G808), His tagged | +Inquiry |
PLK49452H | Recombinant Human PLK4 (6-271), T170D Protein | +Inquiry |
◆ Lysates | ||
PLK4-3102HCL | Recombinant Human PLK4 293 Cell Lysate | +Inquiry |
Related Gene
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewWith PLK4, the sensitivity of the experiment was significantly improved.
Strong anti-pollution ability, not easy to pollute, to ensure the accuracy of the experiment.
The method is very simple, and it is easy to obtain accurate experimental results.
Q&As (6)
Ask a questionThere is an interaction between PLK4 protein and other proteins. For example, it interacts with certain proteins on spindle fibers to regulate chromosome segregation, and with other proteins in signal transduction pathways to regulate cell proliferation and differentiation.
PLK4 protein is mainly responsible for regulating the process of chromosome segregation and cytoplasmic division in cell division. It is associated with the assembly and function of spindle fibers, affecting the accuracy of chromosome segregation and cell division.
Certain biomolecules can be used as molecular markers of PLK4 protein, such as mRNA or protein of PLK4 protein detected in biological samples such as blood and urine. These markers can be used for early diagnosis of disease, prognostic judgment, or monitoring of treatment efficacy.
Therapeutics targeting the PLK4 protein are still in the early stages of research. A number of small molecule inhibitors and antibody drugs have been developed and initially evaluated in laboratories and clinical trials. However, further research and clinical validation of these treatments are needed to determine their safety and efficacy.
Therapeutic strategies for PLK4 protein include inhibition of its activity, regulation of its expression, and gene therapy. For example, the development of small molecule inhibitors or antibody drugs against the PLK4 protein to inhibit its aberrant activity in tumors, or the regulation of PLK4 protein expression through gene knockout or overexpression techniques.
Studies have shown that the abnormal expression of PLK4 protein is associated with the occurrence of a variety of tumors, including but not limited to brain cancer, lung cancer, breast cancer, pancreatic cancer, etc. It may be related to aspects such as proliferation, metastasis, and drug resistance of tumor cells.
Ask a Question for All PLK4 Products
Required fields are marked with *
My Review for All PLK4 Products
Required fields are marked with *
Inquiry Basket