Recombinant Mouse Popdc2 Protein (Ser2-Lys255), N-His tagged

• Cat.No.: Popdc2-6776M
• Product Overview: Recombinant mouse Popdc2 (Ser2-Lys255) fused with the N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Ser2-Lys255
• Description: This gene encodes a member of the Popeye domain containing family of membrane proteins. Proteins of this family contain three helical transmembrane domains and a conserved intracellular Popeye domain. In the adult mouse, this gene is expressed at high levels in cardiac myocytes, and mice deficient for this gene develop stress-induced cardiac pacemaker dysfunction. The protein binds to a two-pore domain potassium channel and recruits it to the plasma membrane. Cyclic adenosine monophosphate negatively regulates this interaction through the Popeye domain. Alternative splicing results in multiple transcript variants.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 30.28 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Popdc2 popeye domain containing 2 [ Mus musculus (house mouse) ]
• Official Symbol: Popdc2
• Synonyms: Popdc2; popeye domain containing 2; Pop2; popeye domain-containing protein 2
• Gene ID: 64082
• mRNA Refseq: NM_022318
• Protein Refseq: NP_071713
• UniProt ID: Q9ES82