Recombinant Mouse Ppard Protein, Myc/DDK-tagged

• Cat.No.: Ppard-5029M
• Product Overview: Purified recombinant protein of mouse full-length peroxisome proliferator activator receptor delta (Ppard), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 50.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppard peroxisome proliferator activator receptor delta [ Mus musculus (house mouse) ]
• Official Symbol: Ppard
• Synonyms: PPARD; peroxisome proliferator activator receptor delta; peroxisome proliferator-activated receptor delta; mPPAR(delta); PPARdelta/beta; nuclear hormone receptor 1; nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; NUC1; NUC-1; Nr1c2; Pparb; PPAR[b]; Pparb/d; PPAR-beta; PPARdelta; PPAR-delta
• Gene ID: 19015
• mRNA Refseq: NM_011145
• Protein Refseq: NP_035275
• UniProt ID: P35396