Recombinant Mouse PPARG Protein Pre-coupled Magnetic Beads

• Cat.No.: PPARG-6969M-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Mouse
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Pparg peroxisome proliferator activated receptor gamma [ Mus musculus ]
• Official Symbol: PPARG
• Gene ID: 19016
• mRNA Refseq: NM_001127330.1
• Protein Refseq: NP_001120802.1
• UniProt ID: P37238

Reviews

09/15/2020

It was reassuring to use a product that adhered to green chemistry principles, reducing our impact on the environment.

06/03/2017

The company's dedication to environmental sustainability reflected positively on the product and our research initiatives.

05/04/2017

We appreciated the option to request modifications or custom formulations to meet our project's requirements.

Q&As

How many isoforms of PPARG are there, and what are their weights?

PPARG has two isoforms, PPARG1 (57 kDa) and PPARG2, a splice variant with an additional 30 amino acids at the N-terminus.

What is the molecular weight of PPARG?

PPARG has two isoforms with molecular weights of 57 kDa and 54 kDa. Modified PPARG is about 67 kDa.

What does PPARG stand for?

PPARG stands for Peroxisome Proliferator-Activated Receptor Gamma.

Is there a mitochondria-localized form of PPARG?

Yes, experimental data suggests a 45 kDa protein immunologically related to PPARG, called mt-PPAR, is located in mitochondria. Its molecular weight is less than PPARG2.

What is the role of PPARG in cellular function?

PPARG is a ligand-activated transcription factor that plays a crucial role in regulating lipid homeostasis, adipogenesis, insulin resistance, and organ development.

What are the known diseases associated with PPARG defects?

Defects in PPARG are associated with familial partial lipodystrophy type 3 (FPLD3), susceptibility to obesity, type 2 insulin-resistant diabetes, hypertension, and colon cancer.

Where is PPARG mainly localized?

PPARG is mainly localized in the nucleus, although it can also be detected in the cytoplasm, exhibiting extra-nuclear/non-genomic actions in certain contexts.