Recombinant Mouse Ppp2r5c Protein, Myc/DDK-tagged

• Cat.No.: Ppp2r5c-5080M
• Product Overview: Purified recombinant protein of mouse full-length protein phosphatase 2, regulatory subunit B', gamma (Ppp2r5c), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 52.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma [ Mus musculus (house mouse) ]
• Official Symbol: Ppp2r5c
• Synonyms: PPP2R5C; protein phosphatase 2, regulatory subunit B (B56), gamma isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform; Band 8A; B56/PP2A gamma; PP2A B subunit isoform B-gamma; PP2A B subunit isoform R5-gamma; PP2A B subunit isoform B56-gamma; PP2A B subunit isoform B-alpha-3; PP2A B subunit isoform PR61-gamma; C85228; AI060890; AW545884; mKIAA0044; D12Bwg0916e; 2610043M05Rik; 2700063L20Rik
• Gene ID: 26931
• mRNA Refseq: NM_001081458
• Protein Refseq: NP_001074927
• UniProt ID: Q60996