Recombinant Full Length Mouse Prkar1a Protein, Myc/DDK-tagged

• Cat.No.: Prkar1a-5114M
• Product Overview: Purified recombinant protein of mouse full-length protein kinase, cAMP dependent regulatory, type I, alpha (Prkar1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Protein Length: 1-381 a.a.
• Description: The encoded protein is a regulatory subunit of the cAMP-dependent protein kinase (PKA) complex, which is responsible for transducing most of the cAMP signals in eukaryotic cells. The inactive PKA complex contains two regulatory and two catalytic subunits. Binding of cAMP dissociates the complex, allowing monomeric catalytic subunits to phosphorylate cytosolic proteins or induce gene expression in the nucleus. Several transcript variants encoding the same protein have been found for this gene.
• Molecular Mass: 43.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Prkar1a
• Synonyms: PRKAR1A; protein kinase, cAMP dependent regulatory, type I, alpha; cAMP-dependent protein kinase type I-alpha regulatory subunit; protein kinase, cAMP dependent regulatory, type 1, alpha; Tse1; Tse-1; RIalpha; 1300018C22Rik
• Gene ID: 19084
• mRNA Refseq: NM_021880
• Protein Refseq: NP_068680
• UniProt ID: Q9DBC7