Recombinant Mouse Prpf6 Protein, Myc/DDK-tagged

• Cat.No.: Prpf6-5149M
• Product Overview: Purified recombinant protein of mouse full-length pre-mRNA splicing factor 6 (Prpf6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
• Molecular Mass: 106.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Prpf6 pre-mRNA splicing factor 6 [ Mus musculus (house mouse) ]
• Official Symbol: Prpf6
• Synonyms: PRPF6; PRP6 pre-mRNA splicing factor 6 homolog (yeast); pre-mRNA-processing factor 6; PRP6 homolog; U5-102 kDa protein; U5 snRNP-associated 102 kDa protein; ANT-1; U5-102K; 1190003A07Rik; 2610031L17Rik; MGC11655; MGC36967; MGC38351
• Gene ID: 68879
• mRNA Refseq: NM_133701
• Protein Refseq: NP_598462
• UniProt ID: Q91YR7