Recombinant Mouse Pspc1 Protein, Myc/DDK-tagged

• Cat.No.: Pspc1-5208M
• Product Overview: Purified recombinant protein of mouse full-length paraspeckle protein 1 (Pspc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Together with NONO, required for the formation of nuclear paraspeckles. Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line. Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 58.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pspc1 paraspeckle protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Pspc1
• Synonyms: PSPC1; paraspeckle protein 1; paraspeckle component 1; mPSP1; PSP1; AI327109; AI449052; 5730470C09Rik
• Gene ID: 66645
• mRNA Refseq: NM_025682
• Protein Refseq: NP_079958
• UniProt ID: Q8R326