Recombinant Mouse Rab11fip3 Protein, Myc/DDK-tagged

• Cat.No.: Rab11fip3-5286M
• Product Overview: Purified recombinant protein of mouse full-length RAB11 family interacting protein 3 (class II) (Rab11fip3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track).
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 123.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rab11fip3 RAB11 family interacting protein 3 (class II) [ Mus musculus (house mouse) ]
• Official Symbol: Rab11fip3
• Synonyms: RAB11FIP3; RAB11 family interacting protein 3 (class II); rab11 family-interacting protein 3; FIP3-Rab11; cytoplasmic adaptor for RAR and TR; Cart1; mKIAA0665; Rab11-FIP3; D030060O14Rik; MGC47508
• Gene ID: 215445
• mRNA Refseq: NM_001162869
• Protein Refseq: NP_001156341
• UniProt ID: Q8CHD8