Recombinant Mouse Rabgap1l Protein, Myc/DDK-tagged
Cat.No. : | Rabgap1l-5338M |
Product Overview : | Purified recombinant protein of mouse full-length RAB GTPase activating protein 1-like (Rabgap1l), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | GTP-hydrolysis activating protein (GAP) for small GTPase RAB22A, converting active RAB22A-GTP to the inactive form RAB22A-GDP. Plays a role in endocytosis and intracellular protein transport. Recruited by ANK2 to phosphatidylinositol 3-phosphate (PI3P)-positive early endosomes, where it inactivates RAB22A, and promotes polarized trafficking to the leading edge of the migrating cells. Part of the ANK2/RABGAP1L complex which is required for the polarized recycling of fibronectin receptor ITGA5 ITGB1 to the plasma membrane that enables continuous directional cell migration. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 43.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rabgap1l RAB GTPase activating protein 1-like [ Mus musculus (house mouse) ] |
Official Symbol : | Rabgap1l |
Synonyms : | RABGAP1L; RAB GTPase activating protein 1-like; rab GTPase-activating protein 1-like; rab6 GTPase activating protein-like; HHL; Hh1; AW049894; mKIAA0471; 5830411O09Rik; 8430421H08Rik; 9630005B12Rik |
Gene ID : | 29809 |
mRNA Refseq : | NM_001038621 |
Protein Refseq : | NP_001033710 |
UniProt ID : | A6H6A9 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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