Recombinant Mouse Rabgef1 Protein, Myc/DDK-tagged

• Cat.No.: Rabgef1-5339M
• Product Overview: Purified recombinant protein of mouse full-length RAB guanine nucleotide exchange factor (GEF) 1 (Rabgef1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
• Molecular Mass: 57.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 [ Mus musculus (house mouse) ]
• Official Symbol: Rabgef1
• Synonyms: RABGEF1; RAB guanine nucleotide exchange factor (GEF) 1; rab5 GDP/GTP exchange factor; rabex-5; Rab5 exchange factor; Ras negative regulator Rabex-5; Ras negative regulator Rabex-5/Rin2; Rin2; Rab5ef; Rabex5
• Gene ID: 56715
• mRNA Refseq: NM_019983
• Protein Refseq: NP_064367
• UniProt ID: Q9JM13