Recombinant Mouse Ramac Protein, Myc/DDK-tagged

• Cat.No.: Ramac-5363M
• Product Overview: Purified recombinant protein of mouse full-length RNA guanine-7 methyltransferase activating subunit (Ramac), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT. Regulates RNMT expression by a post-transcriptional stabilizing mechanism. Binds RNA.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 14.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ramac RNA guanine-7 methyltransferase activating subunit [ Mus musculus (house mouse) ]
• Official Symbol: Ramac
• Synonyms: Ramac; RNA guanine-7 methyltransferase activating subunit; RAM; Ramm; Fam103; Rammet; Fam103a1; 2410047I02Rik; 2610204K14Rik; RNA guanine-N7 methyltransferase activating subunit; RNMT actvating mRNA cap methylating subunit; RNMT-activating mRNA cap methylating subunit; RNMT-activating mRNA cap methyltransferase subunit; RNMT-activating mini protein; family with sequence similarity 103, member A1; protein FAM103A1
• Gene ID: 67148
• mRNA Refseq: NM_025997
• Protein Refseq: NP_080273
• UniProt ID: Q9CQY2