Recombinant Mouse Rassf5 Protein, Myc/DDK-tagged

• Cat.No.: Rassf5-5397M
• Product Overview: Purified recombinant protein of mouse full-length Ras association (RalGDS/AF-6) domain family member 5 (Rassf5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 46.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rassf5 Ras association (RalGDS/AF-6) domain family member 5 [ Mus musculus (house mouse) ]
• Official Symbol: Rassf5
• Synonyms: RASSF5; Ras association (RalGDS/AF-6) domain family member 5; ras association domain-containing protein 5; new ras effector 1; Rap1-binding protein; novel ras effector 1; Ras association (RalGDS/AF-6) domain family 5; regulator for cell adhesion and polarization enriched in lymphoid tissues; Rapl; Maxp1; Nore1; Nore1A; Nore1B; AU042887; 1300019G20Rik; MGC107647
• Gene ID: 54354
• mRNA Refseq: NM_018750
• Protein Refseq: NP_061220
• UniProt ID: Q5EBH1