Recombinant Mouse Rbm38 Protein, Myc/DDK-tagged

• Cat.No.: Rbm38-5412M
• Product Overview: Purified recombinant protein of mouse full-length RNA binding motif protein 38 (Rbm38), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 25.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rbm38 RNA binding motif protein 38 [ Mus musculus (house mouse) ]
• Official Symbol: Rbm38
• Synonyms: Rbm38; RNA binding motif protein 38; Rn; Seb; Seb4; Rnpc1; Seb4l; RNA-binding protein 38; RNA-binding region (RNP1, RRM) containing 1; RNA-binding region-containing protein 1; seb4 mRNA; ssDNA-binding protein SEB4
• Gene ID: 56190
• mRNA Refseq: NM_019547
• Protein Refseq: NP_062420
• UniProt ID: Q62176