Recombinant Mouse Rgs8 Protein, Myc/DDK-tagged

• Cat.No.: Rgs8-5501M
• Product Overview: Purified recombinant protein of mouse full-length regulator of G-protein signaling 8 (Rgs8), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 21 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rgs8 regulator of G-protein signaling 8 [ Mus musculus (house mouse) ]
• Official Symbol: Rgs8
• Synonyms: Rgs8; regulator of G-protein signaling 8; 6530413N01Rik; regulator of G-protein signaling 8
• Gene ID: 67792
• mRNA Refseq: NM_026380
• Protein Refseq: NP_080656
• UniProt ID: Q8BXT1