Recombinant Mouse Rhob Protein, MYC/DDK-tagged
Cat.No. : | Rhob-642M |
Product Overview : | Purified recombinant protein of full-length mouse ras homolog family member B (Rhob), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 22.1 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rhob ras homolog family member B [ Mus musculus (house mouse) ] |
Official Symbol : | Rhob |
Synonyms : | Rhob; ras homolog family member B; Arh6; Arhb; AA017882; rho-related GTP-binding protein RhoB; aplysia ras-related homolog B; ras homolog B; ras homolog gene family, member AB; ras homolog gene family, member B |
Gene ID : | 11852 |
mRNA Refseq : | NM_007483 |
Protein Refseq : | NP_031509 |
UniProt ID : | P62746 |
Products Types
◆ Recombinant Protein | ||
RHOB-601C | Recombinant Cynomolgus Monkey RHOB Protein, His (Fc)-Avi-tagged | +Inquiry |
RHOB-3702R | Recombinant Rhesus Macaque RHOB Protein, His (Fc)-Avi-tagged | +Inquiry |
RHOB-4695R | Recombinant Rat RHOB Protein, His (Fc)-Avi-tagged | +Inquiry |
RHOB-7584M | Recombinant Mouse RHOB Protein, His (Fc)-Avi-tagged | +Inquiry |
RHOB-858C | Recombinant Cynomolgus RHOB Protein, His-tagged | +Inquiry |
◆ Lysates | ||
RHOB-2356HCL | Recombinant Human RHOB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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