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Recombinant Mouse Rhob Protein, MYC/DDK-tagged
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| Cat.No. : | Rhob-642M |
| Product Overview : | Purified recombinant protein of full-length mouse ras homolog family member B (Rhob), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
| Description : | Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. |
| Source : | HEK293T |
| Species : | Mouse |
| Tag : | MYC/DDK |
| Molecular Mass : | 22.1 kDa |
| Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade after receiving vials. |
| Concentration : | >50 μg/mL as determined by microplate BCA method |
| Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Gene Name : | Rhob ras homolog family member B [ Mus musculus (house mouse) ] |
| Official Symbol : | Rhob |
| Synonyms : | Rhob; ras homolog family member B; Arh6; Arhb; AA017882; rho-related GTP-binding protein RhoB; aplysia ras-related homolog B; ras homolog B; ras homolog gene family, member AB; ras homolog gene family, member B |
| Gene ID : | 11852 |
| mRNA Refseq : | NM_007483 |
| Protein Refseq : | NP_031509 |
| UniProt ID : | P62746 |
◆ Recombinant Protein
| RHOB-30284TH | Recombinant Human RHOB | +Inquiry |
| RHOB-2291H | Recombinant Human RHOB, GST-tagged | +Inquiry |
| RHOB-3529H | Recombinant Human Ras Homolog Gene Family, Member B, His-tagged | +Inquiry |
| RHOB-14168M | Recombinant Mouse RHOB Protein | +Inquiry |
| RHOB-858C | Recombinant Cynomolgus RHOB Protein, His-tagged | +Inquiry |
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◆ Lysates
| RHOB-2356HCL | Recombinant Human RHOB 293 Cell Lysate | +Inquiry |
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