Recombinant Mouse Rhob Protein, MYC/DDK-tagged Rhob-642M

Recombinant Mouse Rhob Protein, MYC/DDK-tagged


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Recombinant Mouse Rhob Protein, MYC/DDK-tagged

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Cat.No. : Rhob-642M
Product Overview : Purified recombinant protein of full-length mouse ras homolog family member B (Rhob), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Source : HEK293T
Species : Mouse
Molecular Mass : 22.1 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Rhob ras homolog family member B [ Mus musculus (house mouse) ]
Official Symbol : Rhob
Synonyms : Rhob; ras homolog family member B; Arh6; Arhb; AA017882; rho-related GTP-binding protein RhoB; aplysia ras-related homolog B; ras homolog B; ras homolog gene family, member AB; ras homolog gene family, member B
Gene ID : 11852
mRNA Refseq : NM_007483
Protein Refseq : NP_031509
UniProt ID : P62746

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