Recombinant Mouse Riox2 Protein, Myc/DDK-tagged

• Cat.No.: Riox2-5521M
• Product Overview: Purified recombinant protein of mouse full-length ribosomal oxygenase 2 (Riox2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
• Molecular Mass: 53.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Riox2 ribosomal oxygenase 2 [ Mus musculus (house mouse) ]
• Official Symbol: Riox2
• Synonyms: Riox2; ribosomal oxygenase 2; M; Mina; AI449204; 1810047J07Rik; 2410057H13Rik; 3830408E23Rik; ribosomal oxygenase 2; MYC-induced nuclear antigen; bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; histone lysine demethylase MINA; myc induced nuclear antigen; EC 1.14.11.-
• Gene ID: 67014
• mRNA Refseq: NM_025910
• Protein Refseq: NP_080186
• UniProt ID: Q8CD15