Recombinant Mouse Rtf2 Protein, Myc/DDK-tagged

• Cat.No.: Rtf2-5640M
• Product Overview: Purified recombinant protein of mouse full-length replication termination factor 2 (Rtf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA.
• Molecular Mass: 33.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rtf2 replication termination factor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Rtf2
• Synonyms: Rtf2; replication termination factor 2; Rtfdc; Rtfdc1; AA589417; 1700067C04Rik; 2410001C21Rik; 5730427M17Rik; replication termination factor 2; UPF0549 protein C20orf43 homolog; likely orthologue of H. sapiens chromosome 20 open reading frame 43 (C20orf43); protein RTF2 homolog; replication termination factor 2 domain containing 1; replication termination factor 2 domain-containing protein 1
• Gene ID: 66404
• mRNA Refseq: NM_025542
• Protein Refseq: NP_079818
• UniProt ID: Q99K95