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Recombinant Mouse Scin Protein, Myc/DDK-tagged

Cat.No. : Scin-5714M
Product Overview : Purified recombinant protein of mouse full-length scinderin (Scin), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : Ca2+-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2). In vitro, also has barbed end capping and nucleating activities in the presence of Ca2+. Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles. Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts. Regulates chondrocyte proliferation and differentiation. Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 69.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Scin scinderin [ Mus musculus (house mouse) ]
Official Symbol : Scin
Synonyms : SCIN; scinderin; adseverin; gelsolin-like protein; AW545522
Gene ID : 20259
mRNA Refseq : NM_009132
Protein Refseq : NP_033158
UniProt ID : Q60604

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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