Recombinant Mouse Selp Protein, C-Avi-6His tagged, Biotinylated

Cat.No. : Selp-05M
Product Overview : Biotinylated Recombinant Mouse P-selectin is produced by our Mammalian expression system and the target gene encoding Trp42-­Ala709 is expressed with a Avi, 6His tag at the C-terminus.
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Description : P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family. It consists 768 amino acid (aa). P-selectin is a cell surface glycoprotein expressed by activated platelets and endothelial cells. It induced expression in lung, liver, kidney and heart after endotoxin treatment. Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. it also mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P-selectin interacts with SNX17, PSGL1/SEPL, PODXL2, mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1.
Source : Human Cells
Species : Mouse
Tag : His&Avi
Protein length : Trp42-­Ala709
Endotoxin : Less than 0.1 ng/μg (1 EU/μg)
Storage Buffer : Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Shipping : Ambient
Gene Name : Selp selectin, platelet [ Mus musculus (house mouse) ]
Official Symbol : Selp
Synonyms : P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; PADGEM
Gene ID : 20344
mRNA Refseq : NM_011347
Protein Refseq : NP_035477
UniProt ID : Q01102

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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