Recombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade E, Member 1

• Cat.No.: Serpine1-5319M
• Product Overview: Recombinant Mouse Serpine1was expressed in E. coli (PAI-1) + Insect cell culture (tPA).

Specification

• Cat. No.: Serpine1-5319M
• Description: Mouserecombinant Serpine1complexedto tPA. Mouse sc-tPA is reacted with an excess of mouse Serpine1 stablemutant at physiological pH. The resulting 1:1 molar complex is purified fromthe remaining Serpine1 by affinity chromatography with immobilizedantibodies to mouse tPA.
• Source: E. coli (PAI-1) +Insect cell culture (tPA)
• Species: Mouse
• Form: Frozen liquid in0.4M HEPES + 0.1M NaCl, pH 7.4.
• Purity: > 95% by SDS-PAGEanalysis.
• Endotoxin Level: < 0.1 ng/μg ofprotein.
• Concentration: 1.0 mg/ml
• Storage: Store at-80°C. Stable at -80°C for 1 year from delivery. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: Serpine1

Gene Information

• Gene Name: Serpine1 serine (or cysteine)peptidase inhibitor, clade E, member 1 [ Mus musculus ]
• Synonyms: Serpine1; serine (orcysteine) peptidase inhibitor, clade E, member 1; PAI1; PAI-1; Planh1;plasminogen activator inhibitor 1; PAI; serpin E1; plasminogen activatorinhibitor, type I; endothelial plasminogen activator inhibitor; nexin,plasminogen activator inhibitor type 1; serine (or cysteine) proteinaseinhibitor, clade E, member 1; Plasminogen activator inhibitor-1 precursor(PAI-1) (Endothelial plasminogen activator inhibitor) (PAI)
• Gene ID: 18787
• mRNA Refseq: NM_008871
• Protein Refseq: NP_032897
• UniProt ID: P22777
• Chromosome Location: 5 G2
• Pathway: Adipogenesis; BloodClotting Cascade; Chagas disease (American trypanosomiasis); Complement andCoagulation Cascades; Complement and coagulation cascades; Senescence andAutophagy; TGF Beta Signaling Pathway; p53 signaling pathway
• Function: protease binding;protein binding; serine-type endopeptidase inhibitor activity