Recombinant Mouse Serpine1 Protein (Leu24-Ser402), C-His tagged

• Cat.No.: Serpine1-6802M
• Product Overview: Recombinant mouse Serpine1 (Leu24-Ser402) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Description: Enables serine-type endopeptidase inhibitor activity. Involved in defense response to Gram-negative bacterium; negative regulation of plasminogen activation; and regulation of angiogenesis. Acts upstream of or within several processes, including cellular response to transforming growth factor beta stimulus; placenta development; and regulation of angiogenesis. Located in extracellular space. Is expressed in several structures, including aorta; extraembryonic component; liver; oocyte; and placenta. Used to study Coronavirus infectious disease. Human ortholog (s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); diabetic retinopathy (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human SERPINE1 (serpin family E member 1).
• Source: Mammalian cells
• Species: Mouse
• Tag: C-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 41.69 kDa
• Protein Length: Leu24-Ser402
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 [ Mus musculus (house mouse) ]
• Official Symbol: Serpine1
• Synonyms: plasminogen activator inhibitor 1; PAI; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; plasminogen activator inhibitor, type I; serine (or cysteine) proteinase inhibitor, clade E, member 1; serpin E1; Serpine1; serine (or cysteine) peptidase inhibitor, clade E, member 1; PAI1; PAI-1; Planh1
• Gene ID: 18787
• mRNA Refseq: NM_008871
• Protein Refseq: NP_032897
• UniProt ID: P22777