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Recombinant Mouse Serping1 Protein, His-tagged

Cat.No. : Serping1-281M
Product Overview : Recombinant Mouse Serping1(Val211~Ser331) fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : Serping1 played an important role in many functions.
Source : E. coli
Species : Mouse
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 15.0kDa
Identity : Reconstitute in PBS or others
Protein length : Val211~Ser331
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 [ Mus musculus ]
Official Symbol : Serping1
Synonyms : SERPING1; serine (or cysteine) peptidase inhibitor, clade G, member 1; plasma protease C1 inhibitor; C1 Inh; serpin G1; C1 inhibitor; C1-inhibiting factor; C1 esterase inhibitor; complement component 1 inhibitor; serine (or cysteine) proteinase inhibitor, clade G, member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; C1nh; C1INH;
Gene ID : 12258
mRNA Refseq : NM_009776
Protein Refseq : NP_033906
UniProt ID : P97290

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does the function of SERPING1 protein impact the pathophysiology of HAE? 04/18/2023

SERPING1 protein regulates the activity of C1 esterase inhibitor, which in turn modulates the activity of the complement system, leading to the characteristic symptoms of HAE.

What are the implications of genetic mutations in the SERPING1 gene for HAE patients? 12/08/2022

Genetic mutations in the SERPING1 gene can lead to decreased levels or dysfunctional SERPING1 protein, contributing to the development of HAE.

Can the measurement of SERPING1 protein levels be used to monitor treatment response in HAE patients? 04/25/2021

Yes, monitoring SERPING1 protein levels can help assess the effectiveness of HAE treatments and guide adjustments in therapy if needed.

Are there any other clinical conditions associated with aberrations in SERPING1 protein levels? 03/04/2021

Yes, abnormal levels of SERPING1 protein have been implicated in conditions such as preeclampsia, ischemia-reperfusion injury, and sepsis.

How is the role of SERPING1 protein in HAE treatment evolving with advances in biotechnology? 03/28/2019

Biotechnological advances are enabling the development of novel therapeutic modalities targeting SERPING1 protein, such as gene therapies and monoclonal antibodies.

Customer Reviews (3)

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Reviews
04/22/2023

    With their expertise, I can navigate through experimental hurdles, optimize protocols, and ensure the seamless integration of the SERPING1 protein into my investigations.

    05/14/2020

      The SERPING1 protein showcases unparalleled quality, ensuring it surpasses expectations and satisfactorily addresses my experimental requirements.

      12/02/2019

        Their knowledgeable and responsive team stands ready to address any concerns or challenges I may encounter.

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