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Recombinant Mouse Sfrp2 Protein, His-tagged

Cat.No. : Sfrp2-008M
Product Overview : Recombinant mouse sFRP-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Source : Insect cells
Species : Mouse
Tag : His
Form : Liquid
Molecular Mass : 32.1 kDa
AA Sequence : LFLFGQPDFSYKRSNCKPIPANLQL CHGIEYQNMRLPNLLGHETMKEVLE QAGAWIPLVMKQCHPDTKKFLCSLF APVCLDDLDETIQPCHSLCVQVKDR CAPVMSAFGFPWPDMLECDRFPQDN DLCIPLASSDHLLPATEEAPKVCEA CKTKNEDDNDIMETLCKNDFALKIK VKEITYINRDTKIILETKSKTIYKL NGVSERDLKKSVLWLKDSLQCTCEE MNDINAPYLVMGQKQGGELVITSVK RWQKGQREFKRISRSIRKLQC
Endotoxin : < 1 EU/μg of protein (determined by LAL method)
Purity : > 90% by SDS-PAGE
Applications : SDS-PAGE
Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -87 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/mL (determined by absorbance at 280nm)
Storage Buffer : 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol
Gene Name : Sfrp2 secreted frizzled-related protein 2 [ Mus musculus (house mouse) ]
Official Symbol : Sfrp2
Synonyms : Sfrp2; secreted frizzled-related protein 2; Sdf; Sdf5; AI851596; secreted frizzled-related protein 2; SARP-1; sFRP-2; secreted apoptosis-related protein 1; secreted frizzled-related sequence protein 2; secreted frizzled-related sequence protein 5; stromal cell derived factor 5
Gene ID : 20319
mRNA Refseq : NM_009144
Protein Refseq : NP_033170.1
UniProt ID : P97299

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does SFRP2 expression influence stem cell differentiation and regeneration in various tissues? 01/11/2022

SFRP2 expression plays a significant role in stem cell differentiation, contributing to tissue regeneration and repair processes.

What role does SFRP2 play in the development and progression of cardiovascular diseases, especially atherosclerosis? 08/22/2021

In cardiovascular diseases, SFRP2 plays a role in processes like atherosclerosis, impacting vascular health and disease progression.

What is the impact of SFRP2 on angiogenesis in the context of tumor growth and metastasis? 02/20/2021

SFRP2 influences angiogenesis in tumors, affecting tumor growth and the potential for metastasis.

How does SFRP2 interact with Wnt signaling pathways in cancer development, particularly in colorectal and breast cancers? 11/06/2020

SFRP2 modulates Wnt signaling in cancers, with specific roles in colorectal and breast cancer development, impacting cell proliferation and migration.

How does SFRP2 modulate bone formation and resorption in osteoporosis and other bone diseases? 05/24/2020

SFRP2 is involved in bone metabolism, affecting bone formation and resorption in diseases like osteoporosis.

What are the mechanisms by which SFRP2 contributes to fibrosis in organ systems like the heart and liver? 03/02/2020

SFRP2 contributes to fibrosis in organs like the heart and liver, influencing tissue remodeling and function.

How does the alteration of SFRP2 expression affect adipogenesis and metabolic processes in obesity and diabetes? 11/17/2018

Alterations in SFRP2 expression affect adipogenesis and metabolic functions, linking it to obesity and diabetes pathologies.

Customer Reviews (3)

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Reviews
11/13/2021

    Fast and affordable protein sequencing; great for identifying unknown proteins.

    04/28/2019

      Robust protein-protein interaction assays; pivotal for our experiments.

      02/20/2018

        High-quality protein crystallization; crucial for structural biology studies.

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