Recombinant Mouse Sgpl1 Protein, Myc/DDK-tagged
Cat.No. : | Sgpl1-5828M |
Product Overview : | Purified recombinant protein of mouse full-length sphingosine phosphate lyase 1 (Sgpl1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro-inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP. Seems to play a role in establishing neuronal contact sites and axonal maintenance. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 63.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Sgpl1 sphingosine phosphate lyase 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Sgpl1 |
Synonyms : | SGPL1; sphingosine phosphate lyase 1; sphingosine-1-phosphate lyase 1; mSPL; SPL 1; SP-lyase 1; sphingosine-1-phosphate aldolase; Spl; S1PL; AI428538; D10Xrf456 |
Gene ID : | 20397 |
mRNA Refseq : | NM_009163 |
Protein Refseq : | NP_033189 |
UniProt ID : | Q8R0X7 |
Products Types
◆ Recombinant Protein | ||
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SGPL1-5027R | Recombinant Rat SGPL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
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SGPL1-501H | Recombinant Human SGPL1, His-tagged | +Inquiry |
◆ Lysates | ||
SGPL1-1595HCL | Recombinant Human SGPL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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