Recombinant Mouse Sh3bp4 Protein, Myc/DDK-tagged

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Recombinant Mouse Sh3bp4 Protein, Myc/DDK-tagged

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Cat.No. : Sh3bp4-5842M
Product Overview : Purified recombinant protein of mouse full-length SH3-domain binding protein 4 (Sh3bp4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 108 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Sh3bp4 SH3-domain binding protein 4 [ Mus musculus (house mouse) ]
Official Symbol : Sh3bp4
Synonyms : SH3BP4; SH3-domain binding protein 4; SH3 domain-binding protein 4; BOG25; AI594717; AW227605
Gene ID : 98402
mRNA Refseq : NM_133816
Protein Refseq : NP_598577
UniProt ID : Q921I6
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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