Recombinant Mouse Sh3gl2 Protein, Myc/DDK-tagged

• Cat.No.: Sh3gl2-5845M
• Product Overview: Purified recombinant protein of mouse full-length SH3-domain GRB2-like 2 (Sh3gl2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
• Molecular Mass: 40.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sh3gl2 SH3-domain GRB2-like 2 [ Mus musculus (house mouse) ]
• Official Symbol: Sh3gl2
• Synonyms: SH3GL2; SH3-domain GRB2-like 2; endophilin-A1; SH3p4; endophilin I; endophilin-1; endophilin A1; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2; SH3PA; EEN-B1; Sh3d2a; AI120490; AW555077; 9530001L19Rik; B930049H17Rik
• Gene ID: 20404
• mRNA Refseq: NM_019535
• Protein Refseq: NP_062408
• UniProt ID: Q62420