Recombinant Mouse Shkbp1 Protein, Myc/DDK-tagged

• Cat.No.: Shkbp1-5867M
• Product Overview: Purified recombinant protein of mouse full-length Sh3kbp1 binding protein 1 (Shkbp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 76.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Shkbp1 Sh3kbp1 binding protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Shkbp1
• Synonyms: SHKBP1; Sh3kbp1 binding protein 1; SH3KBP1-binding protein 1; SETA binding protein 1; SETA-binding protein 1; Sb1; B930062H15Rik
• Gene ID: 192192
• mRNA Refseq: NM_138676
• Protein Refseq: NP_619617
• UniProt ID: Q6P7W2