Recombinant Mouse Shoc2 Protein, Myc/DDK-tagged

• Cat.No.: Shoc2-5869M
• Product Overview: Purified recombinant protein of mouse full-length soc-2 (suppressor of clear) homolog (C. elegans) (cDNA clone MGC:31051 IMAGE:4014650), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 58.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Shoc2 Shoc2, leucine rich repeat scaffold protein [ Mus musculus (house mouse) ]
• Official Symbol: Shoc2
• Synonyms: Shoc2; Shoc2, leucine rich repeat scaffold protein; Sur; Sur8; AU017287; mKIAA0862; leucine-rich repeat protein SHOC-2; Ras-binding protein SUR-8; protein soc-2 homolog; protein sur-8 homolog; soc-2 (suppressor of clear) homolog; soc-2-like protein; suppressor of clear, C. elegans, homolog of
• Gene ID: 56392
• mRNA Refseq: NM_019658
• Protein Refseq: NP_062632
• UniProt ID: O88520