Recombinant Mouse Smad2 Protein, Myc/DDK-tagged
| Cat.No. : | Smad2-5950M |
| Product Overview : | Purified recombinant protein of mouse full-length SMAD family member 2 (Smad2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
| Description : | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. |
| Source : | HEK293T |
| Species : | Mouse |
| Tag : | Myc/DDK |
| Molecular Mass : | 52.3 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade after receiving vials. |
| Concentration : | >50 μg/mL as determined by microplate BCA method |
| Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Gene Name : | Smad2 SMAD family member 2 [ Mus musculus (house mouse) ] |
| Official Symbol : | Smad2 |
| Synonyms : | SMAD2; MAD homolog 2 (Drosophila); mothers against decapentaplegic homolog 2; Smad 2; SMAD family member 2; mad-related protein 2; mothers against DPP homolog 2; Madh2; Madr2; mMad2; Smad-2; 7120426M23Rik |
| Gene ID : | 17126 |
| mRNA Refseq : | NM_010754 |
| Protein Refseq : | NP_034884 |
| UniProt ID : | Q62432 |
Products Types
| ◆ Recombinant Protein | ||
| SMAD2-306H | Recombinant Human SMAD2 Protein, His-tagged | +Inquiry |
| Smad2-307M | Recombinant Mouse Smad2 Protein, His-tagged | +Inquiry |
| SMAD2-4146R | Recombinant Rhesus Macaque SMAD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| SMAD2-1915H | Recombinant Human SMAD2 Protein, MYC/DDK-tagged | +Inquiry |
| SMAD2-5266R | Recombinant Rat SMAD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| ◆ Lysates | ||
| SMAD2-001MCL | Recombinant Mouse SMAD2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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