Recombinant Mouse Smad2 Protein, Myc/DDK-tagged

Cat.No. : Smad2-5950M
Product Overview : Purified recombinant protein of mouse full-length SMAD family member 2 (Smad2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
Description : Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 52.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Smad2 SMAD family member 2 [ Mus musculus (house mouse) ]
Official Symbol : Smad2
Synonyms : SMAD2; MAD homolog 2 (Drosophila); mothers against decapentaplegic homolog 2; Smad 2; SMAD family member 2; mad-related protein 2; mothers against DPP homolog 2; Madh2; Madr2; mMad2; Smad-2; 7120426M23Rik
Gene ID : 17126
mRNA Refseq : NM_010754
Protein Refseq : NP_034884
UniProt ID : Q62432

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Smad2 Products

Required fields are marked with *

My Review for All Smad2 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

Stay Updated on the
Latest Bioscience Trends

Copyright © 2023 Creative BioMart. All Rights Reserved.

Terms and Conditions        Privacy Policy