Recombinant Mouse Smurf1 Protein, Myc/DDK-tagged
Cat.No. : | Smurf1-5984M |
Product Overview : | Purified recombinant protein of mouse full-length SMAD specific E3 ubiquitin protein ligase 1 (Smurf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS. Plays a role in dendrite formation by melanocytes. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 83.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Smurf1 SMAD specific E3 ubiquitin protein ligase 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Smurf1 |
Synonyms : | SMURF1; SMAD specific E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase SMURF1; Smad ubiquitination regulatory factor 1; SMAD-specific E3 ubiquitin-protein ligase 1; mKIAA1625; 4930431E10Rik |
Gene ID : | 75788 |
mRNA Refseq : | NM_029438 |
Protein Refseq : | NP_083714 |
UniProt ID : | Q9CUN6 |
Products Types
◆ Recombinant Protein | ||
SMURF1-4169R | Recombinant Rhesus Macaque SMURF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMURF1-467H | Recombinant Human SMURF1, FLAG-tagged | +Inquiry |
SMURF1-4353R | Recombinant Rhesus monkey SMURF1 Protein, His-tagged | +Inquiry |
SMURF1-264Z | Recombinant Zebrafish SMURF1 | +Inquiry |
SMURF1-45H | Recombinant Human SMURF1 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
SMURF1-1647HCL | Recombinant Human SMURF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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