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Recombinant Mouse Snca Protein

Cat.No. : Snca-386M
Product Overview : Recombinant Mouse Snca(1-140 aa) was expressed in E. coli.
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  • Gene Information
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Description : SNCA is associated with human neurodegenerative diseases, where it forms aggregates in nerve tissues. Diseases include Parkinson’s disease, dementia with lewy bodies, and multi-system atrophy, but also other’s disease like Alzheimer’s Disease. Lewy Bodies are well-known cytoplasmic deposits of SNCA in Parkinson’s disease.
Source : E. coli
Species : Mouse
Form : Finally dialysed in pure water, shock frozen in liquid nitrogen at a protein concentration of 2.5 mg/ml
Molecular Mass : 14629 kg/mol
Protein length : 1-140 aa
AA Sequence : GSMDVFMKGLSKAKEGVVAAAEKTK QGVAEAAGKTKEGVLYVGSKTKEGV VHGVTTVAEKTKEQVTNVGGAVVTG VTAVAQKTVEGAGNIAAATGFVKKD QMGKGEEGYPQEGILEDMPVDPGSE AYEMPSEEGYQDYEPEA
Purity : > 98% by SDS-PAGE
Notes : Thawing: Gentle agitation at 37 centigrade. Refreezing is not recommended and should be avoided.
Storage : Store at -80 centigrade
Concentration : 2.5 mg/ml
Gene Name : Snca synuclein, alpha [ Mus musculus ]
Official Symbol : Snca
Synonyms : SNCA; synuclein, alpha; alpha-synuclein; alpha SYN; non-A4 component of amyloid; non-A beta component of AD amyloid; NACP; alphaSYN;
Gene ID : 20617
mRNA Refseq : NM_001042451
Protein Refseq : NP_001035916
UniProt ID : O55042

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can SNCA protein levels in cerebrospinal fluid be used as a diagnostic marker for Parkinson's disease? 10/11/2022

Yes, elevated levels of SNCA protein in cerebrospinal fluid can be indicative of Parkinson's disease.

What potential therapeutic strategies target SNCA protein for Parkinson's disease treatment? 03/27/2022

Therapies may include reducing SNCA aggregation or preventing its misfolding.

Are there any genetic mutations related to SNCA protein that increase the risk of Parkinson's disease? 10/17/2018

Yes, certain mutations in the SNCA gene are associated with familial Parkinson's disease.

How is SNCA protein associated with neurodegenerative diseases? 06/11/2016

Aggregates of misfolded SNCA protein are implicated in various neurodegenerative diseases, including Parkinson's disease.

Are there any ongoing clinical trials investigating SNCA-related therapies? 05/27/2016

Yes, several clinical trials are exploring treatments targeting SNCA protein in Parkinson's disease.

Customer Reviews (3)

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Reviews
08/31/2020

    Its integrity and reliability make it an ideal choice to address the specific objectives of my research.

    03/12/2020

      Their profound knowledge and expertise will undoubtedly help me overcome any challenges that arise, and their prompt assistance ensures a seamless progression of my research.

      10/16/2017

        In addition to the exceptional quality of the protein, the manufacturer's support extends beyond the product itself.

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