Recombinant Mouse Snrpa Protein, Myc/DDK-tagged

• Cat.No.: Snrpa-6004M
• Product Overview: Purified recombinant protein of mouse full-length small nuclear ribonucleoprotein polypeptide A (Snrpa), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 31.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Snrpa small nuclear ribonucleoprotein polypeptide A [ Mus musculus (house mouse) ]
• Official Symbol: Snrpa
• Synonyms: SNRPA; small nuclear ribonucleoprotein polypeptide A; U1 small nuclear ribonucleoprotein A; U1-A; U1 snRNP A; U1 snRNP protein A; protein A of the U1 small nuclear RNA; U1A; Rnu1a1; Rnu1a-1; C430021M15Rik
• Gene ID: 53607
• mRNA Refseq: NM_015782
• Protein Refseq: NP_056597
• UniProt ID: Q62189