Recombinant Mouse Sord Protein, Myc/DDK-tagged

• Cat.No.: Sord-6046M
• Product Overview: Purified recombinant protein of mouse full-length sorbitol dehydrogenase (Sord), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Polyol dehydrogenase that catalyzes the reversible NAD+-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility and protein tyrosine phosphorylation. Has no activity on ethanol. Cannot use NADP+ as the electron acceptor.
• Molecular Mass: 38.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sord sorbitol dehydrogenase [ Mus musculus (house mouse) ]
• Official Symbol: Sord
• Synonyms: SORD; sorbitol dehydrogenase; L-iditol 2-dehydrogenase; sorbitol dehydrogenase 1; Sdh1; Sdh-1; Sodh-1; MGC31355
• Gene ID: 20322
• mRNA Refseq: NM_146126
• Protein Refseq: NP_666238
• UniProt ID: Q64442