Recombinant Mouse Spindoc Protein, Myc/DDK-tagged

• Cat.No.: Spindoc-6096M
• Product Overview: Purified recombinant protein of mouse full-length spindlin interactor and repressor of chromatin binding (Spindoc), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of a number of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway. Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4.
• Molecular Mass: 34.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Spindoc spindlin interactor and repressor of chromatin binding [ Mus musculus (house mouse) ]
• Official Symbol: Spindoc
• Synonyms: Spindoc; spindlin interactor and repressor of chromatin binding; AI8461; AI846148; SPIN-DOC; 1700105P06Rik; spindlin interactor and repressor of chromatin-binding protein; SPIN1-docking protein; uncharacterized protein C11orf84 homolog
• Gene ID: 68229
• mRNA Refseq: NM_001167831
• Protein Refseq: NP_001161303
• UniProt ID: Q05AH6