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Recombinant Mouse STAT6 Protein, His-tagged

Cat.No. : STAT6-01M
Product Overview : Recombinant Mouse Stat6 protein, fused with His-tag, was expressed in E. coli.
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Description : Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in interleukin-4-mediated signaling pathway and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including T-helper 1 cell lineage commitment; mammary gland development; and regulation of nucleobase-containing compound metabolic process. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including 2-cell stage embryo; alimentary system; lower urinary tract; male reproductive system; and olfactory epithelium. Human ortholog(s) of this gene implicated in lipoid nephrosis; prostate carcinoma; and urinary schistosomiasis. Orthologous to human STAT6 (signal transducer and activator of transcription 6).
Source : E.coli
Species : Mouse
Tag : His
Form : PBS buffer, pH 7.4.
Molecular Mass : 95.9 kDa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MSLWGLISKM SPEKLQRLYV DFPQRLRHLL ADWLESQPWE FLVGSDAFCY NMASALLSAT VQRLQATAGE QGKGNSILPH ISTLESIYQR DPLKLVATIR QILQGEKKAV IEEFRHLPGP FHRKQEELKF TTALGRLQHR VRETRLLRES LQQGAKTGQV SLQNLIDPPV NGPGPSEDLA TMLQGTVGDL EATQALVLKR IQIWKRQQQL AGNGTPFEES LAGLQERCES LVEIYSQLQQ EIGAASGELE PKTRASLISR LDEVLRTLVT SSFLVEKQPP QVLKTQTKFQ AGVRFLLGLQ FLGTSAKPPM VRADMVTEKQ ARELSLAQGP GTGVESTGEI MNNTVPLENS IPSNCCSALF KNLLLKKIKR CERKGTESVT EEKCAVLFST SFTLGPNKLL IQLQALSLPL VVIVHGNQDN NAKATILWDN AFSEMDRVPF VVAERVPWEK MCETLNLKFM AEVGTSRGLL PEHFLFLAQK IFNDNSLSVE AFQHRCVSWS QFNKEILLGR GFTFWQWFDG VLDLTKRCLR SYWSDRLIIG FISKQYVTSL LLNEPDGTFL LRFSDSEIGG ITIAHVIRGQ DGSSQIENIQ PFSAKDLSIR SLGDRIRDLA QLKNLYPKKP KDEAFRSHYK PEQMGKDGRG YVSTTIKMTV ERDQPLPTPE PQMPAMVPPY DLGMAPDASM QLSSDMGYPP QSIHSFQSLE ESMSVLPSFQ EPHLQMPPNM SQITMPFDQP HPQGLLQCQS QEHAVSSPEP MLCSDVTMVE DSCLTQPVGG FPQGTWVSED MYPPLMPPTE QDLTKLLLEN QGEAGGSLGS QPLLQPSPYG QSGISLSHLD LRTNPSWLE
Purity : >85% by SDS-PAGE
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Concentration : 0.5 mg/mL
Gene Name : Stat6 signal transducer and activator of transcription 6 [ Mus musculus (house mouse) ]
Official Symbol : STAT6
Synonyms : HIES6; STAT6B; STAT6C; D12S1644; IL-4-STAT
Gene ID : 20852
mRNA Refseq : NM_009284.2
Protein Refseq : NP_033310.2
UniProt ID : P52633

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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