Recombinant Mouse Tbc1d2 Protein, Myc/DDK-tagged

• Cat.No.: Tbc1d2-6304M
• Product Overview: Purified recombinant protein of mouse full-length TBC1 domain family, member 2 (Tbc1d2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 104.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tbc1d2 TBC1 domain family, member 2 [ Mus musculus (house mouse) ]
• Official Symbol: Tbc1d2
• Synonyms: TBC1D2; TBC1 domain family, member 2; TBC1 domain family member 2A; likely ortholog of H. sapiens TBC1 domain family, member 2 (TBC1D2); Gm1037; PARIS1; PARIS-1; BC022630; A630005A06Rik; RP23-117B19.7
• Gene ID: 381605
• mRNA Refseq: NM_198664
• Protein Refseq: NP_941066
• UniProt ID: B1AVH7