Recombinant Mouse Tdrd3 Protein, Myc/DDK-tagged

• Cat.No.: Tdrd3-6349M
• Product Overview: Purified recombinant protein of mouse full-length tudor domain containing 3 (Tdrd3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 82.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tdrd3 tudor domain containing 3 [ Mus musculus (house mouse) ]
• Official Symbol: Tdrd3
• Synonyms: TDRD3; tudor domain containing 3; tudor domain-containing protein 3; 6720468N18; 4732418C03Rik
• Gene ID: 219249
• mRNA Refseq: NM_172605
• Protein Refseq: NP_766193
• UniProt ID: Q91W18