Recombinant Mouse TFRC Protein (Cys89-Phe763), Fc-tagged

• Cat.No.: Tfrc-46M
• Product Overview: Recombinant Mouse TFRC protein (Cys89-Phe763) with a Fc-tag tag was expressed in HEK293

Specification

• Description: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.
• Source: HEK293
• Species: Mouse
• Tag: Fc
• Molecular Mass: The protein has a calculated MW of 101.4 kDa.
• AA Sequence: CKRVEQKEECVKLAETEETDKSETM ETEDVPTSSRLYWADLKTLLSEKLN SIEFADTIKQLSQNTYTPREAGSQK DESLAYYIENQFHEFKFSKVWRDEH YVKIQVKSSIGQNMVTIVQSNGNLD PVESPEGYVAFSKPTEVSGKLVHAN FGTKKDFEELSYSVNGSLVIVRAGE ITFAEKVANAQSFNAIGVLIYMDKN KFPVVEADLALFGHAHLGTGDPYTP GFPSFNHTQFPPSQSSGLPNIPVQT ISRAAAEKLFGKMEGSCPARWNIDS SCKLELSQNQNVKLIVKNVLKERRI LNIFGVIKGYEEPDRYVVVGAQRDA LGAGVAAKSSVGTGLLLKLAQVFSD MISKDGFRPSRSIIFASWTAGDFGA VGATEWLEGYLSSLHLKAFTYINLD KVVLGTSNFKVSASPLLYTLMGKIM QDVKHPVDGKSLYRDSNWISKVEKL SFDNAAYPFLAYSGIPAVSFCFCED ADYPYLGTRLDTYEALTQKVPQLNQ MVRTAAEVAGQLIIKLTHDVELNLD YEMYNSKLLSFMKDLNQFKTDIRDM GLSLQWLYSARGDYFRATSRLTTDF HNAEKTNRFVMREINDRIMKVEYHF LSPYVSPRESPFRHIFWGSGSHTLS ALVENLKLRQKNITAFNETLFRNQL ALATWTIQGVANALSGDIWNIDNEF DKTHTCPPCPAPELLGGPSVFLFPP KPKDTLMISRTPEVTCVVVDVSHED PEVKFNWYVDGVEVHNAKTKPREEQ YNSTYRVVSVLTVLHQDWLNGKEYK CKVSNKALPAPIEKTISKAKGQPRE PQVYTLPPSRDELTKNQVSLTCLVK GFYPSDIAVEWESNGQPENNYKTTP PVLDSDGSFFLYSKLTVDKSRWQQG NVFSCSVMHEALHNHYTQKSLSLSP GK
• Purity: >90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.05 mg/mL
• Storage Buffer: PBS, pH 7.4

Gene Information

• Gene Name: Tfrc transferrin receptor [ Mus musculus ]
• Official Symbol: Tfrc
• Synonyms: TFRC; transferrin receptor; transferrin receptor protein 1; mammary tumor virus receptor 1; TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; Mtvr-1; AI195355; AI426448; AU015758; 2610028K12Rik; E430033M20Rik
• Gene ID: 22042
• mRNA Refseq: NM_011638
• Protein Refseq: NP_035768