Recombinant Mouse Tle2 Protein, Myc/DDK-tagged

• Cat.No.: Tle2-6448M
• Product Overview: Purified recombinant protein of mouse full-length transducin-like enhancer of split 2 (Tle2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
• Molecular Mass: 83.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tle2 transducin-like enhancer of split 2 [ Mus musculus (house mouse) ]
• Official Symbol: Tle2
• Synonyms: TLE2; transducin-like enhancer of split 2, homolog of Drosophila E(spl); transducin-like enhancer protein 2; groucho-related protein; Grg2; mKIAA4188; KIAA4188
• Gene ID: 21886
• mRNA Refseq: NM_019725
• Protein Refseq: NP_062699
• UniProt ID: Q9WVB2