Recombinant Mouse Tmco1 Protein, Myc/DDK-tagged

• Cat.No.: Tmco1-6460M
• Product Overview: Purified recombinant protein of mouse full-length transmembrane and coiled-coil domains 1 (Tmco1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 21.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tmco1 transmembrane and coiled-coil domains 1 [ Mus musculus (house mouse) ]
• Official Symbol: Tmco1
• Synonyms: Tmco1; transmembrane and coiled-coil domains 1; ESTM3; ESTM39; AA109065; AU022572; 1190006A08Rik; 4930403O06Rik; calcium load-activated calcium channel; CLAC channel; transmembrane and coiled-coil domain-containing protein 1
• Gene ID: 68944
• mRNA Refseq: NM_001039483
• Protein Refseq: NP_001034572
• UniProt ID: Q921L3