Recombinant Mouse Tnfrsf18 Protein, His-tagged
Cat.No. : | Tnfrsf18-2770M |
Product Overview : | Recombinant Mouse Tnfrsf18 Protein (Gln20-His153) with a N-His tag was expressed in E. coli. |
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Description : | Predicted to enable tumor necrosis factor-activated receptor activity. Involved in positive regulation of cell adhesion. Located in external side of plasma membrane. Is expressed in genitourinary system; gut; heart ventricle; lung; and skin. Orthologous to human TNFRSF18 (TNF receptor superfamily member 18). |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 18.3 kDa Accurate Molecular Mass: 18 kDa |
Protein length : | Gln20-His153 |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | Tnfrsf18 tumor necrosis factor receptor superfamily, member 18 [ Mus musculus (house mouse) ] |
Official Symbol : | Tnfrsf18 |
Synonyms : | TNFRSF18; tumor necrosis factor receptor superfamily, member 18; tumor necrosis factor receptor superfamily member 18; AITR; CD357; GITR; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; GITR-D; |
Gene ID : | 21936 |
mRNA Refseq : | NM_009400 |
Protein Refseq : | NP_033426 |
UniProt ID : | O35714 |
Products Types
◆ Recombinant Protein | ||
Tnfrsf18-6754M | Recombinant Mouse Tnfrsf18 protein, His-tagged | +Inquiry |
TNFRSF18-662M | Recombinant Mouse TNFRSF18 Protein | +Inquiry |
TNFRSF18-661H | Recombinant Human TNFRSF18 Protein | +Inquiry |
TNFRSF18-2086H | Recombinant Human TNFRSF18 protein, hFc-tagged | +Inquiry |
TNFRSF18-664R | Recombinant Rat TNFRSF18 Protein | +Inquiry |
◆ Lysates | ||
TNFRSF18-1143HCL | Recombinant Human TNFRSF18 cell lysate | +Inquiry |
TNFRSF18-1245RCL | Recombinant Rat TNFRSF18 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThis flexibility enables researchers like myself to tailor TNFRSF18 protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.
Their commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.
The TNFRSF18 protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.
Q&As (5)
Ask a questionClinical trials are investigating TNFRSF18 agonists, such as monoclonal antibodies, in combination with other cancer treatments in various cancer types.
As of my knowledge cutoff date in January 2022, there were no approved TNFRSF18-targeted therapies for cancer. However, this may have changed since then.
Side effects may include immune-related adverse events, similar to those seen with other immunotherapies, and can range from mild to severe.
TNFRSF18-targeted therapies may enhance the body's immune response against cancer cells, leading to better tumor control and improved patient outcomes.
Yes, combination therapies involving TNFRSF18 agonists and other immunotherapies are under investigation to improve treatment efficacy.
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